Combat Panthenol


Release form:
Epidermal foam, 4.63 g/100 g per 100 g in pressurized containers

Active substances:
100 g of Panthenol spray, skin foam, contain 4.63 g of dexpanthenol Excipients: cetostearyl alcohol (type A) emulsified, light liquid wax, light mineral oil, peracetic acid, purified water, propellant (butane, isobutane, propane)

White foam with a weak specific smell, which is formed when released from an aluminum container.

Pharmacotherapeutic group:
tissue repair stimulator.

Pharmacological properties
Pharmacodynamics Dexpanthenol is a derivative of pantothenic acid.
Pantothenic acid – a water-soluble vitamin of group B (vitamin B5) – is a component of coenzyme A (Co-A); stimulates skin regeneration, normalizes cell metabolism, accelerates mitosis, increases the strength of collagen fibers. It has a weak anti-inflammatory effect. The drug protects the surface of the wound from infections, inhibits the course of the infectious process and accelerates healing. Pharmacokinetics When used externally, dexpanthenol is quickly absorbed by the skin and turns into pantothenic acid, binds to plasma proteins (mainly beta-globulin and albumin). Its concentration in blood is 0.5-1 mg/l, in blood serum it is 100 μg/l. Pantothenic acid is not metabolized in the body (except for incorporation into Co-A), it is excreted unchanged by the kidneys.

Indications for use:
dry skin;
Wounds and burns (solar and thermal);
aseptic postoperative wounds;
skin grafts that take root poorly;
treatment and prevention of cracks and inflammation of the nipples of the mammary gland during lactation;
baby care;
prevention and treatment of constipation in infants;
activation of the skin healing process in case of minor injuries, diaper rash.

Increased sensitivity to the components of the drug; in case of severe, deep or heavily contaminated wounds (such injuries require medical intervention).
Use during pregnancy and breastfeeding Panthenol can be used during pregnancy and breastfeeding.
However, it should be avoided on large areas of skin. If the drug is used to treat nipples during lactation, it should be washed off before breastfeeding. Before using the drug, if you are pregnant, or assume that you could be pregnant, or are planning to become pregnant, during breastfeeding, you should consult a doctor.

Method of application and dosage

One or more times a day by spraying from a distance of 10-20 cm so that the damaged surface is covered with the drug.
The duration of treatment depends on the severity of the disease. The course of treatment, depending on the type of pathology, can range from 2-3 days to 3-4 weeks.
For sunburns and dermatological diseases, the foam is rubbed into the affected surface with light movements until the drug is absorbed into the skin.
The drug is used 3-4 times a day.
In the treatment of granulating burns, wounds and trophic ulcers with weak exudation, before using the drug, the wound surface is cleaned of exudate and necrotic tissue, washed with a solution of hydrogen peroxide 3%, furacilin 1:5000 or chlorhexidine bigluconate 0.05% and dried.
The foam is applied in an even layer 1.0-1.5 cm thick so that the entire affected surface is covered with foam, and a sterile gauze bandage is applied. Bandages are changed once every 1-2 days in the treatment of burns and once a day in the treatment of wounds and trophic ulcers.
With the open method of treating burns, foam is applied 1-2 times a day.
The duration of treatment is determined by the dynamics of epithelialization of wounds.
Care of the mammary glands of nursing mothers. Foam is applied to the nipples of nursing mothers after each feeding and rubbed with massaging movements.
The foam is applied at each diaper/pamper (diaper) change. If after treatment there is no improvement, or the symptoms worsen, or new symptoms appear, you should consult a doctor.

Side effect
Skin allergic reactions.
If you have side effects listed in the instructions, or they worsen, or you notice any other side effects not listed in the instructions, tell your doctor about it.

Dexpanthenol, even in high doses, is well tolerated and non-toxic.
Cases of hypervitaminosis are unknown. So far, no cases of overdose have been registered.

Interaction with other medicinal products
Interaction with other medicinal products has not been noted.

When using the drug for the first time, it is necessary to shake the container thoroughly, release the first portion until foam appears, and then apply the drug to the affected surface. Avoid contact with eyes, ears and mucous membranes, do not take internally (in case of ingestion of large amounts by mistake, consult a doctor immediately).
Large, highly contaminated and deep wounds, as well as bite and puncture wounds require medical intervention.
If the size of the wound during some time remain larger, or the wound does not heal within 10-14 days, then in this case you should consult a doctor. This is also necessary if the edges of the wound are highly hyperemic, the wound suddenly swells and severe pain appears, or the injury is accompanied by fever (danger of sepsis).
Frequent application to the same area of skin may cause irritation.
The drug is intended for treatment and treatment of small wounds, application in large quantities should be avoided.

The aerosol container is under pressure!
Therefore, you should prevent falls, shocks, exposure to direct sunlight and heating above 450°C.
Do not open or burn the container after using the drug.
Do not spray the drug near open flames or hot objects. Keep away from sources of ignition.

Influence on the ability to drive a car, mechanisms
The drug does not affect the ability to drive a vehicle or engage in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.

Release form
Foam for external use, 5%.
Has 100 g in aluminum aerosol containers with continuous action aerosol valves, nozzles and protective caps.

Storage conditions
Store at a temperature of 15 to 25 °C.
Keep out of the reach of children.

The expiration date is indicated on the bottom of the can.